It is important to properly configure and secure SQL Server, keep the server well fire-walled and patched and restrict access on the server to only educated IT staff.
Since Microsoft SQL Server communicates over port (1433, default), you must open the port in the firewall.
The SQL Server Browser service lets users connect to instances of the Database Engine that are not listening on port 1433, without knowing the port number. To use SQL Server Browser, you must open UDP port 1434. To promote the most secure environment leave the SQL Server Browser service stopped, and configure clients to connect using the port number.
Configure your antivirus software settings and make sure that you exclude SQL Server binaries, backups and, above all, data files, transaction log files and the quorum disk (in a cluster configuration) from virus scanning.
It is also worth noticing that mixing different types of database implementations (i.e. OLTP vs. OLAP) is NOT recommended. OLTP databases usually have short transactions with a lot of updates whereas reporting databases, such as OLAP and data warehouse systems, have longer data-heavy queries.
M3 BE has mainly an OLTP performance profile. We strongly recommend NOT installing LBI/BPW database on the same instance and database server.